Singapore, Feb 08, 2012: US-based Anacor Pharmaceuticals has announced a positive preliminary results from two safety studies of AN2728, a maximal use systemic exposure (MUSE) study in psoriatic patients and a local tolerability study. The results of these two studies demonstrate that AN2728 Ointment, two percent appears to be safe and well-tolerated when applied to very large body surface areas and that it is well-tolerated when applied to areas of sensitive skin. AN2728 has previously demonstrated safety and efficacy in multiple Phase I and II trials for mild-to-moderate psoriasis and most recently in a Phase 2a study in atopic dermatitis.

"These data confirm the safety of AN2728 and the potential for it to be used on areas of the body that are susceptible to side effects from steroids and tend to be sensitive to irritation from vitamin D analogs," said David Perry, CEO of Anacor Pharmaceuticals. "All of the clinical studies we have done to date on AN2728 in psoriasis and atopic dermatitis support that it could be a potentially safe and effective topical treatment for patients who suffer from mild-to-moderate psoriasis or atopic dermatitis."