Back in 2005, the governing authorities approved on-line medicine trade. Three categories of licenses were issued: B2B, B2C and trading platform. By 2013, there are over 50 on-line drug stores running within China. Compared with mature American and European on-line drug sales, China’s peers clearly develop slowly with merely several on-line stores could make hundreds of millions sales. However, with the prosperity of International and Internet of Things, the fledgling on-line medical service shall have a great future in China.